Friday, October 23 -- Paul Shaffer

Paul Shaffer ("We'll Be Here for the Rest of Our Lives: A Swingin' Show-biz Saga"): You can't really think of David Letterman without thinking about this beloved bandleader. But how did a kid from a remote Canadian town end up being up in show biz? He's here to tell us about that and his new memoir.

Backstreet Boys ("This Is Us"): This group holds the title of being the best-selling pop group of all time, and they're here today to talk about their newest album and to perform the new single "Straight Through My Heart" and their classic "I Want It That Way."

Rachel Guzy ("Bonnie's Kindhearted Kid"): You'll hear all about this young lady's quick thinking in the face of an unimaginable sequence of events. She'll give us her account of how she saved a bus full of children when the driver suffered an unfortunate fate.

More from Friday, October 23 -- Paul Shaffer

Thursday, October 22 -- Tim Roth

Tim Roth ("Lie to Me"): On the FOX show, he plays a psychologist who can read body language and facial expressions to tell if someone is lying. We're hoping he'll tell us the truth on whether it's true that he was training to be a sculptor before the acting bug bit!

Kevin McKidd ("Grey's Anatomy"): Is there a doctor in the house? There is when this handsome actor sits down with Bonnie today! Paging all "Grey's Anatomy" fans: Dr. Owen Hunt is here!

Jeff Dunham ("The Jeff Dunham Show"): He's made quite a mark in the comedy world for someone who talks to himself! This ventriloquist/comedian and his beloved cast of characters; Walter, Peanut and José Jalapeño, are all now starring in their own show on Comedy Central. We're sure that when they're here, one of them will tell us all about it!

"Ask Alice": Bonnie will be freshly back from a trip to Chicago. What fun stories will Alice have to share of her visit? Find out when everyone's favorite mom is back up on webchat.

More from Thursday, October 22 -- Tim Roth

Wednesday, October 21 -- T.R. Knight

T.R. Knight ("Parade"): This actor made headlines during his run at "Grey's Anatomy" for what happened in front of the camera and behind it. He's now returning to the stage in this musical that he'll tell Bonnie all about.

Freddie Highmore ("Astro Boy"): He's been in some big-name films, like "Finding Neverland" and "Charlie and the Chocolate Factory." Now he's lending his voice to this beloved animated character.

Michelle Renee ("I Survived..."): Imagine being at home with your daughter and having three gunmen break in and force you to rob the bank where you work or else they will kill your daughter. For this guest, this nightmare became a chilling reality. Hear her incredible story of survival.

Mail From You Guys: We're shaking out the mailbag and reading all the letters from you guys. Today Bonnie will answer some.

More from Wednesday, October 21 -- T.R. Knight

Tuesday, October 20 -- Alison Sweeney

Alison Sweeney ("Days of Our Lives"/"Biggest Loser"): She's been on "Days of Our Lives" since she was 16 years old, and for the past two years has been hosting the weight loss reality show "Biggest Loser." You "Days" fans won't want to miss her appearance and our "Day of Days" Contest currently running!

Victoria Gotti ("This Family of Mine"): Many of us wouldn't know what it would be like growing up with "The Godfather" as your father, but this former reality show star and daughter of John Gotti knows firsthand -- and wrote a book about her experience.

Greg Proops ("Head Games"): He's the host of this new game show on the Science Channel that challenges contestants' science knowledge with unusual and fun questions. Don't miss when Bonnie plays for charity!

More from Tuesday, October 20 -- Alison Sweeney

Monday, October 19 -- Serena Wiliams

Serena Williams ("On the Line"): She's the #1-ranked female tennis player in the world, and recently made headlines for her reaction to a judge's questionable call at the US Open. Is there a double standard for women in sports? Bonnie talks to her about that and her new book.

Dr. Sanjay Gupta ("Cheating Death"): As the Chief Medical Correspondent for CNN, this doctor has made a name for himself as a health authority. He's here today to discuss swine flu -- and whether you should vaccinate your children. Plus, he'll take questions from our audience.

Mark Decascos & Lacey Schwimmer ("Dancing with the Stars"): He may be the "Chairman" of Kitchen Stadium, but he's on equal footing with the other contestants learning to dance on this hit reality show. See what he's learning from the competition when he and dancing partner Lacey chat with Bonnie.

More from Monday, October 19 -- Serena Wiliams